Skip to main content

Plant-Based Ingredients for Hormonal Acne: Reishi and Saw Palmetto Explained

When people think about acne treatment, they often picture harsh topical products or prescription medication. But for hormonal acne, particularly the kind that flares before your period, the root trigger is often internal. This has led to growing interest in plant-based ingredients that support hormone-related pathways.


Two botanicals frequently discussed in hormone-aware formulations are reishi mushroom and saw palmetto. Both have been studied for their influence on androgen activity, a key driver of hormonal breakouts, below we will discuss how they work.

 

Why androgens matter in hormonal acne

Hormonal acne is closely linked to androgens, including testosterone and DHT, or dihydrotestosterone. Androgens stimulate the sebaceous glands, increasing oil production. In individuals who are more sensitive to androgen activity, this can lead to:

  • Excess sebum
  • Congested pores
  • Deep, cystic breakouts
  • Jawline and chin acne

Importantly, acne is not always caused by high testosterone levels. Often, it relates to:

  • Increased conversion of testosterone to DHT
  • Heightened 5 alpha reductase activity
  • Greater androgen receptor sensitivity

This is where certain plant-derived compounds become relevant.

 

Saw palmetto: Supporting DHT pathways

Saw palmetto is a plant extract traditionally used in men’s health, but it has become increasingly relevant in discussions around hormonal acne. It has been studied for its influence on 5 alpha reductase, the enzyme that converts testosterone into DHT.

DHT is a more potent androgen than testosterone and has a stronger effect on oil glands. By supporting healthy 5 alpha reductase activity, saw palmetto may help regulate the pathways involved in androgen-driven oil production.

For hormone-responsive skin, this is particularly relevant in the luteal phase, when oestrogen declines and androgen influence becomes relatively stronger.

Rather than blocking hormones outright, saw palmetto is better understood as supporting balanced androgen activity.

 

Reishi mushroom: Androgen receptor modulation

Reishi, also known as Ganoderma lucidum, is a medicinal mushroom long used in traditional systems of medicine. Modern research has begun to explore its bioactive compounds, including triterpenoids.

Some preclinical studies suggest that reishi may influence:

  • Androgen receptor signalling
  • 5 alpha reductase activity
  • Inflammatory pathways

Hormonal acne is not purely an oil issue. It is also inflammatory. Reishi’s potential influence on immune and inflammatory signalling adds another layer of relevance.

While research in humans is still developing, reishi is increasingly included in hormone-focused formulations due to its potential role in both androgen modulation and inflammatory balance. Reishi, also considered the calming mushroom, additionally helps to promote stress resilience, calm the nervous system and support mood in PMDD.

 

Why plant-based does not mean weak

There is often a misconception that plant-derived ingredients are less effective than pharmaceutical alternatives. However, many modern medicines originate from plant compounds, the difference lies in approach:

  • Pharmaceuticals are designed to strongly suppress or block pathways.
  • Botanical extracts are typically used to support balance and regulation.

 

For individuals seeking a gentler, longer-term approach to hormonal skin, plant-based ingredients can offer supportive modulation without dramatically altering hormonal function.

 

A balanced approach to hormonal skin

Hormonal acne rarely involves a single hormone or pathway, it often reflects a combination of:

  • Androgen activity
  • Oestrogen fluctuations
  • Inflammatory signalling
  • Gut and hormone interactions

Plant-based ingredients such as saw palmetto and reishi are most effective when used as part of a broader, mechanism-led approach.


The goal is not to eliminate androgens as they are essential hormones. The goal is to support balanced activity so that oil production and inflammation remain within a stable range.